منابع مشابه
Comparative Sequence Analysis of Human and Mouse Promoter Regions
The DNA sequence just adjacent to the transcriptional start sites (TSSs), what we call the promoter, plays an important role in transcription regulation. Although many attempts have been made to detect functional signals in promoter regions aiming to understand the mechanisms of transcription regulation, those attempts remain challenges because the grammars or semantics of promoter sequences ar...
متن کاملTRES: comparative promoter sequence analysis
Comparative promoter analysis is a promising strategy for elucidation of common regulatory modules conserved in evolutionarily related sequences or in genes showing common expression profiles. To facilitate such analysis, we have developed a software tool that detects conserved transcription factor binding sites, cis-elements, palindromes and k-tuples simultaneously in a set of sequences, and t...
متن کاملSequence alignment kernel for recognition of promoter regions
UNLABELLED In this paper we propose a new method for recognition of prokaryotic promoter regions with startpoints of transcription. The method is based on Sequence Alignment Kernel, a function reflecting the quantitative measure of match between two sequences. This kernel function is further used in Dual SVM, which performs the recognition. Several recognition methods have been trained and test...
متن کاملGenome-Wide Analysis of Bacterial Promoter Regions
Identifying prokaryotic promoter sequences is notoriously difficult and for most sequenced bacterial genomes the promoter sequences are still unknown. Since experimental analysis trails behind sequencing, genome-wide computational promoter discovery is often the only realistic way to discover these sequences in newly sequenced bacterial genomes. However, genome-wide samples for promoter discove...
متن کاملSequence and Phylogenetic Analysis of the Untranslated Promoter Regions for HLA Class I Genes.
Polymorphisms located within the MHC have been linked to many disease outcomes by mechanisms not yet fully understood in most cases. Variants located within untranslated regions of HLA genes are involved in allele-specific expression and may therefore underlie some of these disease associations. We determined sequences extending nearly 2 kb upstream of the transcription start site for 68 allele...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2005
ISSN: 1471-2105
DOI: 10.1186/1471-2105-6-s3-p2